New Monkeypox Codes
American Medical Association has published new CPT Codes in response to the Monkeypox virus outbreak. These codes are to be used to report lab testing and vaccinations and are effective as of July 26, 2022.

Lab Code:
When testing for monkeypox, labs should use code 87593 – Infectious agent detection by nucleic acid (DNA or RNA); orthopoxvirus (eg, monkeypox virus, cowpox virus, vaccinia virus), amplified probe technique, each

Vaccine Product Codes:
For vaccinations, there are two (2) new vaccine codes:
90611 – Smallpox and monkeypox vaccine, attenuated vaccinia virus, live, non-replicating, preservative free, 0.5 mL dosage, suspension, for subcutaneous use. The vaccine, Jynneos, which is also called Imvamune or Imnavez, is given in two (2) doses, 28 days apart.
90622 – Vaccinia (smallpox) virus vaccine, live, lyophilized, 0.3 mL dosage, for percutaneous use. Code 90622 was approved by the U.S. Food and Drug Administration for use against the monkeypox virus.

There are no new administration codes. For administration, you should select from codes 90460/90461 Immunization administration through 18 years of age via any route of administration, with counseling by physician or other qualified health care professional or 90471/90472 Immunization administration (includes percutaneous, intradermal, subcutaneous, or intramuscular injections).

The diagnosis code that should be used to report the Monkeypox virus is B04 and the diagnosis code that should be used to report Monkeypox vaccinations is Z23 (encounter for immunization).



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